Antibiotics used with Scaling and Root Planing

Essay by dumbledore311College, Undergraduate November 2014

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Localized Antimicrobial Adjuncts to SRP

Localized Antimicrobial Adjuncts to SRP in Treating Periodontitis Introduction Comment by Owner: This did not need to be here. You could have gone right to the introduction

The topic chosen for further research was localized delivery of antibiotics that are available for hygienist in conjunction with scaling and root planning and its effects on microbes. It is well researched that clinicians leave deposits and biofilm on teeth and root surfaces in pockets greater than 5 mm. In addition, the biofilm can reform in days or weeks after scaling and root planning. Therefore, local delivery of antibiotics offers hygienist measurable and clinical results in the treatment of periodontitis. An antibiotic is defined as an antimicrobial agent that destroys and inhibits growth of bacteria in the mouth. Locally delivered antibiotics maintain a sustained level of the drug in the periodontal pocket for an extended time, helping the patient fight the bacterial challenge (Wilder,2005).

The results of the research will discuss the benefits of minocycline microspheres (Arestin), chlorhexidine gluconate (Perio chip) and doxycycline hyclate gel (Atridox).


The PerioChip is a biodegradable gelatin-based polymer system that contains the active antimicrobial, chlorhexidine gluconate (2.5 mg). Each chlorhexidine-gelatin wafer or chip is positioned subgingivally with collage pliers (Paquette, Emanuel Ryan, and Wilder,2008). Once in place, PerioChip dissolves naturally with no need to remove it. Patient should avoid flossing at the site of PerioChip insertion for 10 days after placement, since flossing could dislodge the chip. Some mild-to-moderate sensitivity during the first week after placement of the chip is normal and spontaneously resolves within days (What is Perio Chip, 2000).

Although pharmacokinetic studies state that chlorhexidine(CHX) is released from the system for 7-10 days in periodontal pockets, microbial studies have shown suppression of the pocket flora for up to 11 weeks...