Genetic Disorder Project on Osteoporosis

Essay by shalzbalzHigh School, 10th gradeA+, February 2009

download word file, 6 pages 5.0

Faulty genes are responsible for many heath problems. These faulty genes are called genetic disorders. Genetic disorders are passed from one generation to another and we have little or no control over them. They are caused when there is a defect in one’s DNA. An example of a genetic disorder is Osteoporosis. This is a disorder caused by the abnormal loss of bone density. Bones become frail, porous, and likely to fracture due to lack of calcium and other minerals. Osteoporosis was first introduced in Britain by Astley Cooper in 1824. Although British surgeon Astley Cooper wrote in 1824 that the skeleton seemed to become more fragile with age, osteoporosis was not fully described in medical texts until the mid 1920's. She made the link between age-related reductions in bone density and fracture risk. Cooper made his discoveries simply through patient observation, not the manipulation of animals. Astley Cooper was the first to introduce the disease, but along the road there were many people who greatly contributed to our knowledge of osteoporosis to this day.

A step that made Osteoporosis better known was made in the 1830s by a French scientist, Jean Georges Chretien Frederic Martin Lobstein. He noticed that some patients' bones were punctured with larger than normal holes, and he created the term osteoporosis (porous bone) to describe such damaged human bone. But Lobstein didn't answer the question of what might be causing these holes to form in bone, or even whether they might be a symptom of disease. One of the major contributors of this disease was Fuller Albright. He concluded that the most common victims of this disease are women over the age of 50, who have been through menopause. In 1984, the National Institutes of Health made the disease more known, and named it as...