HALLUCINOGEN

Essay by Travis BestUniversity, Bachelor'sF, January 1996

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HALLUCINOGEN. While many drugs speed up or depress the central nervous system, there is a class of drugs that distorts how we feel, hear, see, smell, taste, and think. Called hallucinogens because users often hallucinate, or experience nonexistent sensations, these drugs are also known as psychedelic, or mind-bending, drugs. Some hallucinogens come from natural sources; others are made in laboratories. Examples of natural hallucinogens are mescaline, psilocybin, DMT, and marijuana.

Mescaline, which has been used by American Indians in religious ceremonies, comes from the peyote cactus. Psilocybin, also used by the Indians and believed to have supernatural powers, is found in about 20 varieties of mushrooms. Once ingested, psilocybin is converted to psilocin, which is responsible for the drug's hallucinogenic sensations. DMT (dimethyltryptamine) is a short-acting hallucinogen found in the seeds of certain West Indian and South American plants. In the form of snuff, called cohoba, it has been used in religious ceremonies in Haiti.

Marijuana is a plant belonging to the hemp family . The active principle responsible for the drug's effects is tetrahydrocannabinol (THC), obtained from the amber-colored resin of the flowering tops and leaves of the plant. Hashish is also made from this resin.

Of all drugs, synthetic and natural, the most powerful is LSD, or lysergic acid diethylamide. Twenty micrograms, an almost infinitesimal amount, is sufficient to produce a hallucinogenic effect; just 3 pounds (1.4 kilograms) could induce a reaction in all the inhabitants of New York City and London. This extraordinary potency makes LSD especially dangerous since it is usually impossible to determine how much is contained in doses offered by drug dealers.

LSD is chemically derived from ergot, a parasitic fungus that grows on rye and other grains. An odorless, colorless, and tasteless substance, LSD is sold on the street in tablets,