-Hershey and Chase showed that DNA is the hereditary material of phages
-Hershey and Chase labeled protein in a T2 phage with a radioactive tag
-Then they labeled DNA in a separate batch of phage with a radioactive isotope
-Both batches of tagged phages were allowed to infect separate batches of E.Coli bacteria
-Afterwards, both sets of E. Coli. were placed in separate blenders to shake loose any parts of the phages that remained outside the bacterial cells
-The mixtures were then place in separate centrifuges and spun around to force the bacterial cells to form a pellet at the bottom of the centrifuge
-The viruses and parts of viruses remained in the supernatant
-Hershey and Chase found that the radioactively labeled proteins were found in the supernatant which contained viral particles
-Protein of the phage didn't enter the bacteria
-Bacteria infected with tagged DNA contained radioactivity
-Showed that DNA of the virus is injected into host cell and cause the bacteria to make new viral DNA and proteins
-DNA is hereditary material
-Griffith used two varieties of a bacterium
-One was harmless and other was pathogenic
-Griffith's experiment
-He inject a mouse with a pathogenic strain and it died
-Then he injected a mouse with a harmless strain and it lived
-Then he injected the mouse with cell remains of heat killed pathogenic strain and it lived
-Then he killed the pathogenic bacteria with heat and mixed the cell remains with living bacteria of the harmless strain and injected it into a mouse
-The mouse died and he found that some of the living cells were converted to the pathogenic form
-Experiment showed that some chemical substance caused the change of the living nonpathogenic substances into pathogenic substances
-Griffith called this change of the harmless DNA...
Good
I like that you have put notes on here as it helps others like myself to study. Thankyou x
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