Essays Tagged: "Caco-2"

PERMEABILITY OF HYDROPHILIC MODEL DRUGS MODEL DRUGS ACROSS 2/4/A1 INTESTINAL EPITHELIAL CELL MONOLAYERS MODEL DRUGS ACROSS 2/4/A1 INTESTINAL EPITHELIAL CELL MONOLAYERS

nd discriminated more accurately between the molecules of intermediate molecular weight compared to Caco-2 cells.These results indicated that 2/4/A1 cells could be used as a model for hydrophilic drug ... minimize expensive and sometimes controversial animal studies.Human colorectal carcinoma cell line Caco-2 is nowadays the most widely used and the best explored model for drug intestinal transport (H ...

(14 pages) 138 0 3.9 Jan/1996

Subjects: Science Essays > Chemistry