Biology- Artificial Blood

Essay by BaaBaa May 2014

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MAB 2.3.4 and 2.3.5

Analyse information from secondary sources to identify the products extracted from donated blood and discuss the uses of these products.

Products

Uses of these products

Red Blood Cells (RBC)

RBCs help to carry more oxygen. RBCs may also be used to help replace cells lost following significant bleeding.

Platelet Concentrate

Platelets are essential for the coagulation of blood and are used to treat bleeding caused by conditions or diseases where the platelets are not functioning properly.

Fresh Frozen Plasma (FFP)

FFP is mostly used to provide blood components that coagulate the blood. FFP contains all coagulation elements in normal amounts and is also free of red cells, white blood cells and platelets. It is used is used in treatments such as warfarin therapy (blood thinning) or when massive transfusions have taken place to provide a clotting effect.

Cryoprecipitate Anti-Haemophilic Factor

Cryoprecipitate AHF is a concentrate of clotting proteins and is used for the treatment of von Willebrand disease (similar to haemophilia), replacement of the clotting proteins, fibrinogen, Factor XIII and Factor VIII when no other option is successful.

Analyse and present information from secondary sources to report on progress in the production of artificial blood and use available evidence to propose reasons why such research is needed.

Investigate the following substances before answering the questions below.

Category (based on function)

Artificial substance

Blood volume expanders

Crystalloids and colloids

Oxygen carriers

Modified red blood cell antigen preparations

Cell-free haemoglobin preparations (HBOC's)

Liposome- enclosed haemoglobin (microcapsules)

Perfluorocarbon emulsions

Coagulants

Not available yet

Products for immune defence

Not available yet

What is artificial blood?

Artificial blood is a product made to mimic or act like a substitute for red blood cells which could be transfused into patients to temporarily provide some of the essential life-giving functions of blood until...